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Product Code : 150
SUTENT contains the Drug / Molecule Sunitinib Malate.
USAGE & DESCRIPTION :
SUTENT has used for the treatment of Gastrointestinal Stromal Tumor after disease progression on or intolerance to Imatinib Mesylate. It is also indicated for the
treatment of Advance Renal Cell Carcinoma.
International Brand Name
1*30 (BOTTLE) 1*7(STRIP)
CAPSULES (IN PLASTIC BOTTLE & STRIP )
12.5 MG,25 MG & 50 MG
Sunitinib inhibits cellular signaling by targeting multiple receptor tyrosine kinases (RTKs).These include all receptors for platelet–derived growth factor
(PDGF–Rs) and vascular endothelial growth facto rreceptors (VEGFRs), which play a role in both tumor angiogenesis and tumor cell proliferation.
The simultaneousinhibition of these targets therefore leads to both reduced tumor vascularization and cancer cell death, and ultimately tumor shrinkage.
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